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Gastro-intestinal Stromal Tumour (GIST)

Risk Factors

The factors that increase the risk of GISTs are:

  • Older age: GISTs are rare in people below the age of 40 years. It is more commonly found in people above the age of 50 years.
  • Neurofibromatosis type 1: Patients suffering from this condition have abnormally high cell growth. Thus, such patients have tumors all over the body. The tumor may affect the nerves and cause abnormalities in the eyes, skin, bones, and other body parts. People with this condition are at increased risk of GISTs.
  • Familial GIST syndrome: People with this condition have an increased risk of developing GISTs, especially at a younger age.
  • Carney-Stratakis syndrome: People with Carney-Stratakis syndrome have an increased risk of developing GISTs, especially at a younger age. Such people are also at increased risk of developing other nerve tumors.

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